TFA PROMOTED FOR BIOACTIVE SYNTHESIS OF 3, 3′- (PHENYL METHYLENE) BIS (1H-INDOLE) DERIVATIVES.
A. Hemarao, B. Pryanka and Dr. N. Krishna Rao*
ABSTRACT
An efficient, mild and inexpensive TFA catalyst was used for the synthesis of derivatives of 3, 3?- (Phenyl methylene) bis (1H-indole). These derivatives synthesized from indole and substituted aromatic aldehyde in protic solvent under reflux condition. The characterization of the titled compounds evaluated by spectral data (1HNMR, 13NMR & LCMS). In addition to the compounds study in biological properties.
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