BIOACTIVE SYNTHESIS OF N-ALKYL DERIVATIVES OF ACRIDONES ANALOGOUS
C. Satya, B. Priyanka and Dr. N. Krishna Rao*
ABSTRACT
Five series of N-alkyl substituted acridones such as10-benzyl-9-(3,4-dimethoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione derivatives have been designed and synthesized using an efficient methodology from suitable acridones intermediates such as. 9-(3,4-dimethoxyphenyl)-3,3,6,6-tetramethyl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-dione which is obtained from3,4-dimethoxy benzaldehyde, dimedone and Ammonium chloride. In addition to the study of antimicrobial activity.
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