Abstract

*Saman Anwar, Uzma, Ayesha Shayan, Ramsha Fatima, Rida Zainab, Bushra Shamim

ABSTRACT

Agenesis of the gallbladder and cystic duct is one of the biliary system's rarest malformations, with a reported frequency of 0.007% to 0.027%. It may present as asymptomatic condition that is typically discovered as an incidental finding on imaging modalities. There are also symptomatic instances where patient may present with symptoms like biliary colic that may be linked to cholelithiasis, cholecystitis or cholangitis misleading to various investigations and treatments. The clinical diagnosis of agenesis of the gallbladder is quite difficult since it is an exceptionally infrequent congenital condition with masked clinical and radiologic characteristics. Here, we discuss the case of a 27-year-old female who arrived to the emergency department with complain of right upper quadrant pain, jaundice, and abnormal bowel habits for few months, aggraveted for past one week. An ultrasound of her upper abdomen revealed the absence of GB, which was verified by her CT scan and MRCP. Gallbladder agenesis is a relatively rare condition that could require needless diagnostic procedures and treatments. The gold standard test is the MRCP. Despite its benign nature, smooth muscle relaxants are chosen for conservative treatment in symptomatic patients. This study's objective is to discuss the most crucial aspects of gallbladder agenesis and to help clinicians in the early diagnosis detect GB agenesis as soon as possible to prevent catastrophic events and misleading to various investigations.