International Journal Of Modern
Pharmaceutical Research

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An International Peer Reviewed Journal for Science & Pharmacy Professional

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2319-5878
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Abstract

GENOTOXIC AND HAEMATOLOGICAL EFFECT OF COMMONLY USED INSECTICIDE ON FISH HETEROPNEUSTES FOSSILIS

Subhashree Jagyanseni*, Somanath Sahoo and Satya NarayanSahoo

ABSTRACT

During last three to four decades application of synthetic pesticides in agricultural field to increase agricultural production, has been increased tremendously. Pesticides in agricultural runoff affect all the aquatic organisms. Acephate is an organophosphate insecticide applied to food crops, citrus trees, on golf courses. The result from this study reveals that Acephate had some genotoxic and haematological effect on Heteropneustes fossilis. The fishes were exposed to sublethal concentrations (90% of LC50 of 24hr) of Acephate. Micronucleus assay was carried out after 24, 48, 72and 96hours to analyze micronuclei. The number of micronuclei at 72h was maximum. For haematology fishes were exposed to the chemical for one week. It was determined that Acephate caused a decrease in haemoglobin(Hb), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC) and red blood cells(RBC) levels and increase in white blood cells level.

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