Abstract

Archana Suresh*, Sumeena Beevi S., Dr. Arya M. S. and Prof. Dr. Shaiju S. Dharan

ABSTRACT

Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) is a deadly adverse drug reaction with recognizable signs and symptoms such as skin rashes, fever, leukocytosis with eosinophilia or atypical lymphocytes, lymph node enlargement and liver or renal dysfunction. The pathogenesis of DRESS is related to an aberrant immunological response. Due to its uncommon nature and unusual clinical presentation, DRESS is frequently misdiagnosed. The most often used first line treatment is the use of systemic corticosteroids. Each physician who treats acute cases should be familiar with the clinical presentation and be able to begin the appropriate measurements due to the potentially fatal consequences. Here we describe the case of a patient admitted in our hospital for DRESS syndrome after administration of sulfasalazine.