Abstract

Dr. Yussra Khattri*, Dr. Rida Zainab Ghaloo, Dr. Rabia Ahmed Siddiqui, Dr. Khubab Khalid, Dr. Rabiya Siraj, Dr. Bushra Shamim

ABSTRACT

While comparing with the rest of the organs of the body, brain is less commonly involved organ in tuberculosis. Features of cerebral tuberculosis include meningitis, encephalopathy, arteriopathy, abscess, infarct or Tuberculoma. Intracranial Tuberculoma is an uncommon but an important finding. However, in patients with no previous history of tuberculosis, these Tuberculoma when solitary can be confused as primary brain lesion. Multiple case reports have been published in literature where Tuberculoma were reported as malignant brain lesions. Here we present a strangely similar but radiologically different case scenario, in which 40 years old patient, initially diagnosed with tuberculoma, came out to as multicentric glioma on follow up imaging and histopathology. ? Background: According to WHO, at least one-third of the world’s population is infected with M. tuberculosis. Radiological imaging of tuberculomas can be non-specific and differentiating them from other intracranial brain lesions ? Case presentation: 40 years old patient, initially diagnosed as tuberculoma, proved to be multicentric glioma on histopathology. ? Conclusions: In an endemic country, tuberculoma is one of the top differential diagnosis of ICSOL. Definite diagnosis can be made by excisional biopsy, or by treating the patient with a complete course of anti-tubercular chemotherapy and monitoring the tumor response.