ETIOLOGICAL STRUCTURE, ANTIBACTERIAL RESISTANCE OF PATHOGENS AND CLINICAL COURSE OF HOSPITAL PNEUMONIA IN PREMATURE INFANTS
M.V. Kushnareva*, Kh.M. Markhulia, E. D. Balashova and G. M. Dementyeva
ABSTRACT
We conducted a study of the etiological structure of nosocomial "ventilator-associated" pneumonia (VAP) and the clinical course of the disease in 100 premature newborns. There were revealed violations of the respiratory and cardiovascular systems, kidneys, the development of infectious toxicosis, changes in peripheral blood and urine. Possible complications are identified. VAP pathogens were represented by grampositive and gram-negative bacteria, as well as Candida spp. The cause of nosocomial pneumonia were associations of 2 and less often 3 types of bacteria in 35% of premature infants. 39.4% of newborns developed a secondary infection with a change in pathogen. At the same time, Pseudomonas aerugimosa, Stenotrophomonas maltophilia, coagulase-negative Staphylococcus, Klebsiella pneumoniae were most often isolated. More than half of the bacteria were resistant to many antibiotics and retained sensitivity only to individual drugs.
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