Abstract

Dnyanai P. Dafar, Gaurav M. Wadhankar, Devesh A. Nagphase, Mrunal M. Choudhary, Samiksha P. Dafar, Vaibhav P. Uplanchiwar and Renuka K. Mahajan*

ABSTRACT

Colon medicines can focus specific pharmaceuticals or peptides to the colonic areafor the treatment of a variety of disorders. While ignoring systemic absorption andany negative effects. In order for new pharmaceutical formulations to reach thecolon, a thorough understanding of natural and synthetic or semisynthetic polymersis required. Colon drug administration is critical for the local treatment of a widerange of bowel disorders such as ulcerative colitis, Crohn's disease, amoebiasis,colonic malignancy, local therapy of colonic pathologies, and systemic delivery ofprotein and peptide medicines. Colonic medication administration is beneficial inthe treatment of natural asthma, angina, and arthritis. Direct medicationadministration to the colon is more effective for the treatment of colonic disorder. .such as endorectal cancer and ulcerative colitis Drug that demolishes the acidicregion of the stomach and is absorbed by the impacted in the colon. The purpose ofthis article is to provide insight into the design and assessment of medicationdelivery systems. The architecture and physiology of the lower gastrointestinal tractare described in this article. This review article contains a thorough examination ofcolon disorders, variables influencing medicine absorption, and various colonmethods.